Strychnos mostueoides is a shrub growing from 2 - 3 metres tall[
The plant is harvested from the wild for local medicinal use.
Africa - Medagascar.
Forests near river banks, at elevations from sea-level up to 500 metres, exceptionally to 1,000 metres[
A decoction of the aerial parts is taken to treat malaria[
Eight indole alkaloids have been identified from the root bark: normacusine B, caracusine VII, strychnofendlerine, spermostrychnine, strychnobrasiline, deacetylstrychnobrasiline, malagashine and malagashanine. Chemically normacusine B belongs to the corynanthean class of alkaloids, the other compounds belong to the strychnine class. Normacusine B is also found in Rauvolfia, Tabernaemontana and Vinca spp. It is sympatholytic and its hypotensive activity is stronger than that of reserpine, which is commonly used against high blood pressure[
Malagashanine has been shown to have promising chemosensitizing activity against chloroquine-resistant strains of the malaria parasite Plasmodium falciparum[
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