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Useful Tropical Plants

Holarrhena pubescens

Wall.

Apocynaceae

+ Synonyms

Chonemorpha antidysenterica G.Don

Chonemorpha pubescens (Wall.) G.Don

Echites adglutinatus Burm.f.

Echites antidysentericus Roth

Echites pubescens Buch.-Ham.

Elytropus pubescens (Wall.) Miers

Holarrhena antidysenterica pubescens (Wall.) J.L.Stewart & Brandis

Holarrhena codaga G.Don

Holarrhena febrifuga Klotzsch

Holarrhena fischeri K.Schum

Holarrhena glaberrima Markgr.

Holarrhena glabra Klotzsch

Holarrhena macrocarpa (Hassk.) Fern.-Vill.

Holarrhena malaccensis Wight

Holarrhena perrotii Spire

Holarrhena pierrei Spire

Holarrhena tettensis Klotzsch

Holarrhena villosa Aiton ex Loudon

Nerium sinense Hunter ex Ridl.

Physetobasis macrocarpa Hassk.

Common Name: Conessi

Holarrhena pubescens
Flowers and leaves
Photograph by: Vinayaraj
Creative Commons License
Holarrhena pubescens Holarrhena pubescens Holarrhena pubescens Holarrhena pubescens Holarrhena pubescens

General Information

Conessi is a deciduous shrub or tree with fragrant white flowers and abundant white latex in all its parts. It grows up to 10 metres tall[
266
Title
Flora of China
Publication
 
Author
 
Website
http://flora.huh.harvard.edu/china/
Publisher
Missouri Botanical Garden Press; St. Louis.
Year
1994
ISBN
 
Description
An excellent, comprehensive resource in 25 volumes. In addition to the botanical information the flora also gives basic information on habitat and some uses. An on-line version is also available.
].
An important medicinal plant in the tropics, it is gathered from the wild for its wide range of medicinal and other uses[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. The plant is sometimes cultivated for medicinal purposes, the root bark is sold in local markets, whilst the plant is also cultivated in India as an ornamental for its attractive flowers[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

Known Hazards

None known

Botanical References

200
Title
The New RHS Dictionary of Gardening. 1992.
Publication
 
Author
Huxley. A.
Publisher
MacMillan Press
Year
1992
ISBN
0-333-47494-5
Description
Excellent and very comprehensive, though it contains a number of silly mistakes. Readable yet also very detailed.
,
266
Title
Flora of China
Publication
 
Author
 
Website
http://flora.huh.harvard.edu/china/
Publisher
Missouri Botanical Garden Press; St. Louis.
Year
1994
ISBN
 
Description
An excellent, comprehensive resource in 25 volumes. In addition to the botanical information the flora also gives basic information on habitat and some uses. An on-line version is also available.

Range

Eastern Africa, Indian subcontinent, China, through Myanmar to Indo-China.

Habitat

Montane forests at elevations of 500 - 1,000 metres[
266
Title
Flora of China
Publication
 
Author
 
Website
http://flora.huh.harvard.edu/china/
Publisher
Missouri Botanical Garden Press; St. Louis.
Year
1994
ISBN
 
Description
An excellent, comprehensive resource in 25 volumes. In addition to the botanical information the flora also gives basic information on habitat and some uses. An on-line version is also available.
]. Dry evergreen to dry deciduous forest, scrub woodland, savannah, or in rocky localities, often near watercourses, at elevations up to 1,500 metres[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

Properties

Medicinal Rating *  *  *
Other Uses Rating *  *  *
HabitDeciduous Tree
Height10.00 m
Cultivation StatusCultivated, Ornamental, Wild

Cultivation Details

Though sensitive to frost, the plant recovers easily from damage[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Succeeds on a wide range of soils[
310
Title
Plant Resources of Southeast Asia
Publication
 
Author
 
Website
http://proseanet.org/
Publisher
 
Year
0
ISBN
 
Description
Lots of information on the uses of the plants of SE Asia.
]. Plants can stand slight shade but develop best when growing in full light[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. Established plants are drought tolerant[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The tree coppices well and can survive bush fires by producing sucker shoots from burned-down stumps[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. Juvenile plants are more susceptible to damage by fire than older ones[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Natural reproduction is abundant owing to regular and copious seeding from an early age, comparative immunity of the plant to damage by animals and its power of recovery from injury[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. Seeds, that are dispersed by wind germinate during the early rains, and seedlings attain 10 - 15 cm by the end of the first year[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. In subsequent years, growth is more rapid, the mean annual diameter increment being 7 - 8 mm. In India, early height increment of Holarrhena pubescens is low, only 10 - 15 cm/year under natural conditions[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Established plants are fast-growing[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

Edible Uses

None known

Medicinal

The stem bark and root bark have a long history of traditional use in the treatment of amoebic dysentery throughout the distribution area of the plant[
266
Title
Flora of China
Publication
 
Author
 
Website
http://flora.huh.harvard.edu/china/
Publisher
Missouri Botanical Garden Press; St. Louis.
Year
1994
ISBN
 
Description
An excellent, comprehensive resource in 25 volumes. In addition to the botanical information the flora also gives basic information on habitat and some uses. An on-line version is also available.
,
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. The stem bark is listed in the Pharmacopoeia of India. Although slow in action compared with emetine, it is less toxic and can be administered orally[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. The seeds or bark are sometimes adulterated with those of Wrightia tinctoria, which do not have the same medicinal properties, although both show antibacterial activity[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Considerable research has been carried out into the medical applications of these plants, most of which has tended to bear out its traditional uses.
The stem bark, root bark and seeds yield more than 40 alkaloids. The highest concentration is found in the stem bark and root bark with up to 4.3%, but only 0.4% has been reported for flowering plants. The leaves contain 1 - 1.5% and the seeds 0.6 - 1.8%. According to the Pharmacopoeia of India, the bark should contain about 2% alkaloids[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Most of the alkaloids of the stem bark and root bark are steroid alkaloids derived from conanine or the closely related conamine, which also occur in other Holarrhena species. The main alkaloid of the stem bark and root bark is conessine; other compounds are norconessine (kurchine), conessimine, kurchamine, kurchessine, kurcholessine, conimine, conamine and holarrhenine[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The leaves contain mainly steroid alkaloids derived from pregnane, such as holarrhimine, holaphyllamine, holamine and holaphylline, as well as the alkaloid triacanthine (an adenine derivative). Various amino-glycosteroids are also present in the leaves. These substances contain an amino-sugar and in some of them, e.g. holarosine and holacurtine, the steroidal part of the molecule is a cardenolide[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The seeds contain conessine, norconessine, conamine and conarrhimine[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Conessine has sedative, central nervous system depressant, cardiac depressant, antipyretic and analgesic activities. It also has significant anti-amoebic activity, but it needs to be used with caution because it can produce neurological problems such as vertigo, tremors, insomnia, agitation or anxiety. Conessine also shows antibacterial and antifungal activities against a range of human pathogens in vitro[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Several other steroidal alkaloids also show antibacterial and antifungal activities[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The steroid alkaloids present in the stem bark and root bark have hypotensive activity and are simultaneously local anaesthetic and spasmolytic, but they are also cardiotoxic[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Triacanthine also has hypotensive activity, but is also cardiotonic, antispasmodic and a respiratory analeptic. In addition, triacanthine stimulates the development of mature red blood cells[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Many of the pregnane derivatives can be used as a starting material for the partial synthesis of pharmaceutical steroids, such as adrenocortical hormones (corticosteroids) and sex hormones (e.g. oestrogens, progestrogens and androgens)[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Holamine, holaphyllamine and holaphylline show significant anti-inflammatory properties[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Aqueous extracts of the root bark, stem bark or leaves have relatively low toxicity[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The alcoholic extract of the fruit showed anticancer activity against human epidermoid carcinoma of the nasopharynx in tissue culture[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The aqueous extract of the fruits exhibited hypoglycaemic effects[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Different extracts of the seed or bark showed significant antibacterial and antifungal activities against a wide range of human pathogens, including several antibiotic-resistant strains[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. The bark extract also shows antiplasmodial activity[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
A stem bark decoction showed anti-ulcerogenic effects in different models of gastroduodenal ulcers. It also showed antimicrobial activity against enterohaemorrhagic Escherichia coli strains[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

The bark has anthelmintic, astringent, febrifugal, stomachic and tonic properties[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
A hot decoction of the stem bark is used as a gargle to treat toothache[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The bark and the leaves are applied externally to treat scabies, boils, ulcers and haemorrhoids[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. A powder prepared from the roots and leaves is administered to stop haemorrhages after childbirth and nose bleeding[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The oil from the seeds is considered to possess similar properties to the bark[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

The root is said to be abortifacient, antidote, aphrodisiac, galactagogue and laxative[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. An infusion is taken to stimulate milk production, to treat constipation, asthma, abdominal pains and infertility[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. When boiled in milk, it is applied against snakebites and is used in the treatment of venereal diseases[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

The leaves, pounded in water, are taken to cure stomach-ache[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

The juice from the fruit is taken to treat cough[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

Agroforestry Uses:

A pioneer species, it quickly invades open spaces[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. The plant may prove useful for the reforestation of deforested land in comparatively dry regions, especially because it is not readily browsed even by goats[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. In India the species is successfully intercropped with field crops[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

Other Uses

A dye similar to henna is extracted from the leaves[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

The wood ash is used as a mordant[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

The floss from the seeds is used for stuffing pillows[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

Conessine, an alkaloid found in the plant, was found to possess a wide range of disruptive activities against 4 insect species, and showed potential as a larval growth inhibitor, sterilant and antifeedant in laboratory tests[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

The wood is moderately soft and white, turning yellowish or pinkish with age[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. It has a straight grain and fine and even texture; there is no distinction between sapwood and heartwood[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. The wood is easy to saw and machine and fairly durable under cover[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. Popular for turning and carving, it is used to make small articles such as combs, picture frames, carved boxes, toys, spoons, knives, walking sticks and beads, and sometimes for furniture and ploughs[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
The pulp from the wood has been used to make paper[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].

Propagation

Seed - direct sowing or raising seedlings in a nursery both work well. Fresh seeds have a high percentage of germination, but in seeds more than one year old the viability is low[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
]. The seed usually germinates in 2 - 3 weeks[
299
Title
Protabase - Plant Resources of Tropical Africa.
Publication
 
Author
 
Website
http://www.prota.org
Publisher
 
Year
0
ISBN
 
Description
An excellent on-line database with detailed information on over 3,200 species of useful plants of Africa.
].
Cite as: Tropical Plants Database, Ken Fern. tropical.theferns.info. 2019-05-23. <tropical.theferns.info/viewtropical.php?id=Holarrhena+pubescens>

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